. The Cleveland medical journal . nge. The next day the patients condition was about the same; pulse 92,temperature 994 to 1004°. Another blood culture was made and thistime two c. c. of a sterile solution of sodium citrate was firstaspirated into the syringe to prevent coagulation. On Sept. 21, the blood culture was negative. The patients conditionwas about the same, temperature to ° and pulse 98. Recallingthe rapid coagulation of the blood, and finding that the blood was sterile,I decided to determine the coagulation time of the blood, the technic ofwhich will be described lat


. The Cleveland medical journal . nge. The next day the patients condition was about the same; pulse 92,temperature 994 to 1004°. Another blood culture was made and thistime two c. c. of a sterile solution of sodium citrate was firstaspirated into the syringe to prevent coagulation. On Sept. 21, the blood culture was negative. The patients conditionwas about the same, temperature to ° and pulse 98. Recallingthe rapid coagulation of the blood, and finding that the blood was sterile,I decided to determine the coagulation time of the blood, the technic ofwhich will be described later. The result was that the blood coagulatedin 45 seconds; the normal average being one minute, 45 seconds. Thecoagulation time of the control was one minute, 50 seconds. From these findings, I decided to administer citric acid internallyfor the purpose of diminishing the coagulability of the blood, and therebypreventing the further formation of thrombosis, and possibly hastening CHART-1 too 2oo too o© £* m ^Ho 103 102 100 HI. 2 SEPTEMBER ocTOBea 15 16 !7 18 19 20 21 22 23 24 25 26 27 28 29 30 I 2 3 4 5 6 7 8 9 10 ItTEMPERATURE- •——g SYMPTOMS-* • C04GUUT/0^»- -- - • This shows the increase in the coagulation time of the blood and aconcomitant drop in the temperature and improvement in the symptoms. the dissolution of the already-formed thrombus. I therefore prescribedone dram of citric acid, dissolved in a glass of water, three times a day. On Sept. 23, the patient felt much better; swelling reduced as faras the left knee after five doses of citric acid; temperature to 99° ;pulse 80; coagulation time of the blood one minute, 15 seconds. On Sept. 25, the swelling was reduced above the left knee and abovethe right ankle; left thigh not so tense; temperature °; pulse 82;coagulation time of the blood one minute, 30 seconds. On Sept. 27, the swelling was completely reduced on the left side andup to the knee on the right side; temperature ° ; pulse 80;


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectmedicine, bookyear191