. A laboratory manual and text-book of embryology. Embryology. 2 54 THE DEVELOPMENT OF THE VASCULAR SYSTEM and staining qualities of their cytoplasmic granules, the myelocytes give rise to three types of granular leucocytes: i. Neutrophiles, or leucocytes with a finely granular cytoplasm which is neutral in its staining reactions, coloring slightly with both acid and basic stains. In development, their nuclei take up an eccentric position and become crescentic, horse-shoe shaped, or in the older stages moniliform (three or four pieces linked together). As it changes in form the nucleus undergo
. A laboratory manual and text-book of embryology. Embryology. 2 54 THE DEVELOPMENT OF THE VASCULAR SYSTEM and staining qualities of their cytoplasmic granules, the myelocytes give rise to three types of granular leucocytes: i. Neutrophiles, or leucocytes with a finely granular cytoplasm which is neutral in its staining reactions, coloring slightly with both acid and basic stains. In development, their nuclei take up an eccentric position and become crescentic, horse-shoe shaped, or in the older stages moniliform (three or four pieces linked together). As it changes in form the nucleus undergoes pyknosis and stains in- tensely. Neutrophiles are produced in the bone marrow of the embryo during the fifth month. In the human adult they form 70 to 72 per cent, of the leuco- cytes in normal circulation. 2. Eosinophilcs, or coarsely granular leucocytes, are characterized by their large cytoplasmic granules which stain intensely red with eosin. In development the nucleus becomes bilobed. Eosinophiles form 2 to 4 per cent, of the leucocytes in normal human blood. /â¢''^'' According to Weidenreich â -'-':'â '' ':â¢'' (Arch. f. mikr. Anat., vol. 82, pp. 'â â¢:':'[^^'^''^fSzh 2S2-2S6), the eosinophilic gran- '.'â 'â ' 'â â â â¢r^l^ ules are not endogenous but are fragments of red blood corpuscles which have been ingested by the leucocytes, or are formed from hemoglobin derivatives. Bader- scher (Amer. Jour. Anat., 1013, vol. 15, pp. 69-86) finds in the vicinity of degenerating muscle fibers in salamanders numer- ous eosinophiles. Also during trichiniasis in man, when there is extensive degeneration of muscle fibers, the number of eosinophiles in the blood becomes greatly increased. Downey (Anat. Record, vol. 8, p. 135, 1914) finds that the granules of eosinophilic myelocytes dif- ferentiate from a non-granular cytoplasm. These basophilic granules become Please note that these images are extracted from scanned page images that may have been di
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