The Journal of laboratory and clinical medicine . O^tiA, 2 Srr^sf XWi^ Fig. .^.—Made directly after Fig. 4. mitial smaller dose. These results appear to be perfectly constant for all of thephenanthrene derivatives and possibly for a few of the other series, especiall}-narcotine. It is also found that this failure of the bronchioles and bladder torespond well to a second injection of the drug holds good in the case of thebronchioles for any other member of the opium alkaloids, , in the case heregiven m which the f^rst contraction was due to heroine, then a second injectionof n-orphine.
The Journal of laboratory and clinical medicine . O^tiA, 2 Srr^sf XWi^ Fig. .^.—Made directly after Fig. 4. mitial smaller dose. These results appear to be perfectly constant for all of thephenanthrene derivatives and possibly for a few of the other series, especiall}-narcotine. It is also found that this failure of the bronchioles and bladder torespond well to a second injection of the drug holds good in the case of thebronchioles for any other member of the opium alkaloids, , in the case heregiven m which the f^rst contraction was due to heroine, then a second injectionof n-orphine. or thebaine, or. perpnine. willnot cause a second contrac- Peripheral Action of Opium Alkaloids 869 tion, proiided the initial contraction ^cas maximal. If the first contraction \vassmall (dose submaximal) then the injection of a second much larger dose may
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Keywords: ., bookcentury1900, bookdecade1910, booksubject, booksubjectmedicine
