Transactions of the Royal Society of Edinburgh . t1). After both dosesthere was a greaterincrease in the biliarysecretion than was at all likely to have been caused by the same quantity of water. (See Experiment 7.)Necropsy.—The taraxacum had passed along nearly the whole length of the small intestine. Most of the fluid had been absorbed. There was no evidence of purgative action. Experiment 43a. Small dog that had fasted eighteen hours.—120 grains of solid extract of taraxacum in 15cc. of water were injected into theduodenum (t, fig. 43a), and thisdose was repeated in two-and-a-half hours. Th


Transactions of the Royal Society of Edinburgh . t1). After both dosesthere was a greaterincrease in the biliarysecretion than was at all likely to have been caused by the same quantity of water. (See Experiment 7.)Necropsy.—The taraxacum had passed along nearly the whole length of the small intestine. Most of the fluid had been absorbed. There was no evidence of purgative action. Experiment 43a. Small dog that had fasted eighteen hours.—120 grains of solid extract of taraxacum in 15cc. of water were injected into theduodenum (t, fig. 43a), and thisdose was repeated in two-and-a-half hours. The increase of thebiliary secretion after the seconddose was trivial; but after theAn examination of the Fig. 43.—Secretion of bile before and after taraxacum, t, 180 grains ; t, 120grains of solid extract of taraxacum in 25 cc. of water were injected intothe duodenum. (The triangles and dotted lines indicate the mean of thehigh and low readings in order that a conclusion regarding the effect ofthe substance may be more easily arrived at.). Fig. 43a.—Secretion of bile before and after taraxacum. 120grains of solid extract of taraxacum in 15 cc. of water in-jected into the duodenum at t and t. first it was considerable, though of short durationintestine at death revealed no purgative action. From these experiments it may be concluded that taraxacum is a veryfeeble hepatic stimulant, a conclusion that is in harmony with clinical experience,although the observations on man—from the nature of the case—have yieldednothing perfectly definite. We think it unnecessary to detail these two experi-ments more fully. Action of Nitro-hydrochloric Acid. The dilute nitro-hydrochloric acid employed by us was prepared by mixing3 cc. nitric acid with 4 cc. hydrochloric acid, and after an interval of twenty- PHYSIOLOGICAL ACTIONS OF DRUGS ON THE SECRETION OF BILE. 191 four hours, adding 25 cc. water ( British Pharmacopoeia). The dose for aman is from 5 to 20 minims. The employment of th


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