. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. 684 Dysentery Pathogenesis.—Schaudinn was the first to prove the pathogenic action of the organism. He inspissated the evacuations of a case suffering from dysentery, so that it contained considerable numbers of encysted amebas. When this was fed to kittens they died in two weeks with the typical lesions of dysentery. Musgrave and Clegg had less satisfactory results with cats, dogs, and other laboratory animals, but were quite satisfied with the results
. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. 684 Dysentery Pathogenesis.—Schaudinn was the first to prove the pathogenic action of the organism. He inspissated the evacuations of a case suffering from dysentery, so that it contained considerable numbers of encysted amebas. When this was fed to kittens they died in two weeks with the typical lesions of dysentery. Musgrave and Clegg had less satisfactory results with cats, dogs, and other laboratory animals, but were quite satisfied with the results secured with monkeys, which took the disease and sometimes died. The lesions resembled, but were less severe than those in man. Musgrave and Clegg would not admit that there were non-pathogenic intestinal amebas, but this was not in accord with the work of any other in- vestigators, and was strongly opposed by Craig,* who found both Secondary abscesses Falcifonn ligament. Small a .1 - Secondary abscess in Main abscess Lymphatic spigelian lobe gland Fig. 269.—Multiple amebic abscesses of the liver (J. E. Thompson, in Interna- tional Climes, vol. II, 14th Series, J. B. Lippincott Co., Publishers). varieties, and though he was never able to infect animals with Entamoeba coli, was successful with the pathogenic varieties, and succeeded in infecting 50 per cent, of the kittens he esqjerimented upon, by injecting the amebas into the rectum. Lesions.—The gross morbid appearances of the intestinal lesions in both forms of dysentery are sufficiently distinct in typical cases to enable an experienced pathologist to differentiate them, yet not sufficiently distinct to make them easy of description. The one great characteristic feature of the amebic dysentery is abscess of the Hver which occurs in nearly 25 per cent, of the oases, but which almost never occurs in bacillary dysentery. The distinct and somewhat rigid ectoplasm of the Entamceba histolytica is supposed to make it easy fo
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