. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. INHIBITORS OF PROTEIN SYNTHESIS 11. 40 60 Time (h) 20 40 60 Time (h) 80 100 Figure 5. Attachment of larvae in the presence or absence of emetine or anisomycin as a function of time following addition of GABA. Cu 200 were placed in 10 ml rifampicin-treated seawater in triplicate, as described in Materials and Methods. Following a 30-min incubation with or without emetine (A and B) or a 2-h incubation with or without anisomycin (C and D), GABA was added to the samples indicated, and the mean percentage of the larvae showing at
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. INHIBITORS OF PROTEIN SYNTHESIS 11. 40 60 Time (h) 20 40 60 Time (h) 80 100 Figure 5. Attachment of larvae in the presence or absence of emetine or anisomycin as a function of time following addition of GABA. Cu 200 were placed in 10 ml rifampicin-treated seawater in triplicate, as described in Materials and Methods. Following a 30-min incubation with or without emetine (A and B) or a 2-h incubation with or without anisomycin (C and D), GABA was added to the samples indicated, and the mean percentage of the larvae showing attachment was scored at the times indicated. Standard deviations for all points, assayed in triplicate, were <4<V (A) 8-day-old larvae treated with or without 10 * M GABA and 9 juA/ emetine. No emetine or GABA (diamonds); emetine with no GABA (rectangles); no emetine, plus GABA (triangles); emetine plus GABA (circles). (B) 8-day-old larvae treated with or without 10~3 A/ GABA and 9 nM emetine. No emetine or GABA (diamonds); emetine with no GABA (rectangles); no emetine, plus GABA (triangles); emetine plus GABA (circles), (C) 10-day-old larvae treated with or without 10" A/GABA and 200 pM anisomycin. No anisomycin or GABA (diamonds); anisomycin, with no GABA (rectangles); no anisomycin, plus GABA (triangles); anisomycin plus GABA (circles). (D) 10-day-old larvae treated with or without 10 ' A/ GABA and 200 ^M anisomycin. No anisomycin or GABA (diamonds); anisomycin with no GABA (rectangles); no anisomycin, plus GABA (mangles); anisomycin plus GABA (circles). biotics. These lipophilic groups may facilitate entry into cells and diffusion through tissues. This lipid solvent-like effect also might account for the weak settlement-inducing activity of these antibiotics, analogous to that reported by Pennington and Hadneld (1989) for some organic sol- vents. Puromycin contains only one methoxy group, and fusidic acid contains one acetoxy group. Puromycin, which was not an eff
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
