A system of human anatomy, general and special . duced two, which are a little larger than the cells in figure a. * The same cartilage, still nearer the seat of ossification; each single cell of B hasgiven birth to four, five, or six cells, which form clusters. These clusters become largertowards the right of the figure, and their cells more numerous and larger, J7^ of aninch, long diameter. t The same cartilage at the seat of ossification; the clusters of cells are arranged incolumns; the intercellular spaces between the columns being 7_i?tr of an inch in the riffht of the figure o
A system of human anatomy, general and special . duced two, which are a little larger than the cells in figure a. * The same cartilage, still nearer the seat of ossification; each single cell of B hasgiven birth to four, five, or six cells, which form clusters. These clusters become largertowards the right of the figure, and their cells more numerous and larger, J7^ of aninch, long diameter. t The same cartilage at the seat of ossification; the clusters of cells are arranged incolumns; the intercellular spaces between the columns being 7_i?tr of an inch in the riffht of the figure osseous fibres are seen occupying the intercellular spaces, atfirst bounding the clusters laterally, then splitting them longitudinally and encirclingeach separate cell. The greater opacity of the right hand border is due to a threefoldcause, the increase of osseous fibres, the opacity of the contents of the cells, and the mul-tiplication of oil globules. In the lower part of the figure some attempt has been madeto show the texture of the The cells composing the cluster lie 50 DEVELOPEMENT OF BONE. transversely with regard to its axis. In the first instance they areclosely compressed, but by degrees are parted by a thin layer of inter-cellular substance, and each cluster is separated from neighbouringclusters by a broader layer (^Vf °f inch) of intercellular are the changes which occur in cartilage preparatory to theformation of bone. Ossification is accomplished by the formation of very fine and deli-cate fibres within the intercellular substance: this process commencesat the punctum ossificationis and extends from that point throughevery part of the bone, in a longitudinal direction in long, and in aradiated manner in flat bones. Starting from the punctum ossifi-cationis, the fibres embrace each cluster of cells, and then sendbranches between the individual cells of each group. In this mannerthe network, characteristic of bone, is formed, while the cell
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Keywords: ., bookcentury1800, bookdecade1840, booksubjectanatomy, bookyear1847
