. Ciba Foundation symposium on drug resistance in micro-organisms: mechanisms of development. Drug resistance in microorganisms. 310 P. Alexander, S. F. Cousens and K. A. Stagey coil up the molecule (see Table IV) and only after very exten- sive reaction is there a fall in molecular weight (this will be discussed on p. 315). With a monofunctional reagent such REAGENT ESTERIFICATION 5*. 49% 2200 1950 Phenylalanine ^ mustard 20 /o Bisepoxypropyl ^ ether 42/o 920 875 300 â ^ 6/ sin 72 Fig. 8. Light scattering plots (the reciprocal of the scattering at each angle is plotted as a function of that a
. Ciba Foundation symposium on drug resistance in micro-organisms: mechanisms of development. Drug resistance in microorganisms. 310 P. Alexander, S. F. Cousens and K. A. Stagey coil up the molecule (see Table IV) and only after very exten- sive reaction is there a fall in molecular weight (this will be discussed on p. 315). With a monofunctional reagent such REAGENT ESTERIFICATION 5*. 49% 2200 1950 Phenylalanine ^ mustard 20 /o Bisepoxypropyl ^ ether 42/o 920 875 300 â ^ 6/ sin 72 Fig. 8. Light scattering plots (the reciprocal of the scattering at each angle is plotted as a function of that angle), for DNA treated with various alkylating agents. pg,w, the radius of gyration which is obtained from the slope of the corresponding line, is a measurement of the extension in space of the DNA molecule after reaction. The molecular weight is inversely proportional to the intercept. as propylene oxide no change in shape or molecular weight is observed, proving that esterification of the phosphate groups alone is not sufficient to coil up the molecule. Electron microscope photographs (Fig. 9) also reveal the. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation; Wolstenholme, G. E. W. (Gordon Ethelbert Ward); O'Connor, Cecilia M. (Cecilia Mary), 1927-. Boston, Little, Brown
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