. Quarterly journal of experimental physiology and cognate medical sciences. Fig. 4.—Tracing from the cornu of a rats uterus which had been kept in an ice-chest for threedays. Between the two marks extract of corpus luteum was acting upon the uterus. Noticeits stimulant action. (The signals should be shifted a little to the left.) In rare cases the effect of Ringer extract of corpus luteum, whetherfresh or dried, produced, instead of increase of tone and increased rapidityof the rhythmic contractions, the opposite effect, viz. diminution of tone,which might amount to complete loss of tone, and


. Quarterly journal of experimental physiology and cognate medical sciences. Fig. 4.—Tracing from the cornu of a rats uterus which had been kept in an ice-chest for threedays. Between the two marks extract of corpus luteum was acting upon the uterus. Noticeits stimulant action. (The signals should be shifted a little to the left.) In rare cases the effect of Ringer extract of corpus luteum, whetherfresh or dried, produced, instead of increase of tone and increased rapidityof the rhythmic contractions, the opposite effect, viz. diminution of tone,which might amount to complete loss of tone, and diminution in height, or Influence of Corpus luteum Extracts upon Plain Muscle. 8 Itagaki Such a result is shown even abolition of the rhythmic fig. 5. The existence of pregnancy does not appear to have any specific in-fluence on the effect produced by corpus luteum extract upon the uterusof the rat. Usually the effect is that of increase of tone and increase ofrate of rhythm of the individual contractions, but in one case out of fourwhich were investigated inhibition was produced instead of increase. Sixty-seven experiments were made in all on the rats uterus. Of thesesixty-three were from non-pregnant animals. In fifty-three cases an in-creased contraction was produced. In seven the result was inhibition. Inthe remaining three no perceptible change was caused. Experiments upon the Rabbits Uterus. As a sreneral rule the cornu of the rabbits uterus is too stiff and thickto be used as a whole, and in these cases the record was made from alongitudinal strip of the wall. In seven cases the uterus was taken fromnon-pregnant animals, in three from pregnan


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