. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . on contain numerous leuco-cytes, constituting in some instances what appears to be leuco-cytic thrombi. One section was stained for bacteria, but nonewere found. The process as a whole is to be interpreted as an acutehemorrhagic inflammation of the embryonic structures. Thelarge number of leucocytes undergoing fragmentation indi-cates that the inflammatory irritant was of a severe nature,and had acted with a considerable degree of intensity, as isnot only shown
. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . on contain numerous leuco-cytes, constituting in some instances what appears to be leuco-cytic thrombi. One section was stained for bacteria, but nonewere found. The process as a whole is to be interpreted as an acutehemorrhagic inflammation of the embryonic structures. Thelarge number of leucocytes undergoing fragmentation indi-cates that the inflammatory irritant was of a severe nature,and had acted with a considerable degree of intensity, as isnot only shown by the rich immigration of leucocytes, but thesevere retrogressive changes which they have undergone. No. 135. Ovum, 105 x 65 x 65 mm.; embryo, C. R., 9 mm. Dr. Mosely, Baltimore. The ovum was sent fresh to the laboratory and hardened instrong formalin. It is fairly smooth, its walls being thin andthe villi are wanting. Upon opening it I found it filled com-pletely with a gelatin-like mass which is neither fibrous norgranular. Within this mass there is an atrophic embryostanding upon a thin umbilical cord. The entire chorion is. Fig. 135a.—Embryo upon a mass of magma within the coelom. One-halfnatural size. 200 MALL. [Vol. XIX. lined with the amnion. The head of the embryo is atrophic,the body being shaped like a grain of wheat. The extremitiesare more rudimentary on the right side than on the left. The sections of the embryo show the cord distended, thebrain almost completely destroyed and the mesoderm of thetop of the head converted into a mass of mucoid tissue. Thehead end of the chorda is greatly hypertrophied, being con-verted into a mucoid tumor. On either side of this? tumorthere are two large cartilages, normal in structure. Fartherheadwards, buried deep in the mesoderm, there are two addi-tional pearl-like bodies, which, on account of their appearanceas well as by their being encircled by an oval zone of pigmented QDQ Fig. 135b, c, d.—Three views of the embryo. Nat
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