Electro-physiology electrophysiolog02bied Year: 1896-98 FIG. 170.—a, b, Incomplete tetanus of frog's gastrocnemius on excitation of the cord (divided above) with a rapid succession of induction shocks. Single and previously ineffective opening shocks then excite strongly, if led iu at the part of the cord that has just been tetanised, by the same electrodes. ineffective can be made to act by protracted and immediately antecedent tetanisation (Biedermann, 37). A7'. CHANGES PEODUCED IN NERVE BY ACTIVITY No less difficult than the establishment of the specific excitability of the nerve is the


Electro-physiology electrophysiolog02bied Year: 1896-98 FIG. 170.—a, b, Incomplete tetanus of frog's gastrocnemius on excitation of the cord (divided above) with a rapid succession of induction shocks. Single and previously ineffective opening shocks then excite strongly, if led iu at the part of the cord that has just been tetanised, by the same electrodes. ineffective can be made to act by protracted and immediately antecedent tetanisation (Biedermann, 37). A7'. CHANGES PEODUCED IN NERVE BY ACTIVITY No less difficult than the establishment of the specific excitability of the nerve is the Question whether (as seems a priori the more probable) the course of the excitatory process in the nerve is associated with metabolism, and in what degree. Two methods are here conceivable. It might be possible to demonstrate altera- tions in the chemical composition of the nervous substance either directly by means of prolonged excitation, or indirectly by investigating the laws of fatigue, and recovery, in the nerve. As regards the first question, it is even harder to decide this point in nerve than in muscle, owing partly to its smaller bulk, and partly


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