. Pathogenic microörganisms; a practical manual for students, physicians, and health officers . inexperienced,Negri bodies are structured, more intensely staining, and more 1, 3, and -4 are stained by fuehsin-methylene blue mixture, whichstains Negri bodies (NB) red -with blue granules, nucleus (NDC) of nervecells blue, and red-blood cells yello-w (RB). Fig. 2 is stained by Giemsasmixture, which stains Negri bodies a robins egg blue -with red granules,nucleus of nerve cells red, and red-blood cells salmon pink. RABIES 563 Morphology of the Negri Bodies.^—^The largest forms me
. Pathogenic microörganisms; a practical manual for students, physicians, and health officers . inexperienced,Negri bodies are structured, more intensely staining, and more 1, 3, and -4 are stained by fuehsin-methylene blue mixture, whichstains Negri bodies (NB) red -with blue granules, nucleus (NDC) of nervecells blue, and red-blood cells yello-w (RB). Fig. 2 is stained by Giemsasmixture, which stains Negri bodies a robins egg blue -with red granules,nucleus of nerve cells red, and red-blood cells salmon pink. RABIES 563 Morphology of the Negri Bodies.^—^The largest forms measured areabout 18/i and the smallest about They are round, oval, oblong,triangular, or ameboid. The latter are more numerous in the fixedvirus of rabbits and guinea-pigs. Their structure is shown especiallywell in smears. Whatever the variety or species of animal infected,the bodies present the same general characteristic structure; i. e., ahyaline-like cytoplasm with an entire margin, containing one or morechromatin bodies having a more or less complicated and Fig. 196.—Negri body showing central chromatin with ring of small granules. X 2000. Their structure varies to a certain extent with their size. In fixedvirus, with an occasional exception, only tiny forms are found. Theseare rounded or sometimes wavy in outline, as if possessing slight ameboidmotion, sometimes elongated, extending along the rim of the host-cellnucleus, or along one of the nerve fibrils, as if moving there; witheosin and methylene blue they take a delicate light magenta stain,very similar to that taken by the small serum globules in the of the organisms, however, show a small chromatin granule,situated more or less eccentrically, sometimes on the very rim of thebody. In the larger forms the granule is large, in the smaller it cannotalways be seen; some of the larger forms show from two to severalgranules and occasionally there is a body with the definit
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