An experimental study of sleep (from the Physiological Laboratory of the Harvard Medical School and from Sidis Laboratory) . ises so high that the cell no longer reacts. In respect tothat stimulus the katabolic, active, waking state ceases andis replaced by the anabolic, sleeping states. The cell maythus be awake to all other stimulations, but in regard tothe special stimulus it is asleep. We may say that the cellis asleep partially. When the liberation of energy hasreached the maximum point, and the thresholds are raised ^ Whenever by a stimulus applied to an irritable substance, thepotential
An experimental study of sleep (from the Physiological Laboratory of the Harvard Medical School and from Sidis Laboratory) . ises so high that the cell no longer reacts. In respect tothat stimulus the katabolic, active, waking state ceases andis replaced by the anabolic, sleeping states. The cell maythus be awake to all other stimulations, but in regard tothe special stimulus it is asleep. We may say that the cellis asleep partially. When the liberation of energy hasreached the maximum point, and the thresholds are raised ^ Whenever by a stimulus applied to an irritable substance, thepotential energy there stored up is liberated the following phenomenamay be observed: (1) A so-called latent period of variable durationduring which no effects of stimulation are manifest; (2) A very briefperiod during which the effect of stimulation reaches a maximum; (3) Aperiod of continued stimulation during which the effect diminishes inconsequence of the using up of the substance containing the potentialenergy—, a period of fatigue; (4) A-period after the stimulation hasceased in which the effect slowly passes The curve drawn by a muscle in tetanic contraction, as shown iuthe diagram, illustrates this phenomenon. Thus, if AD represents theduration of the stimulation, AB indicates the latent period, BC the periodof contraction, CD the period of fatigue under stimulation, and DE theafter-effect of stimulation showing itself as a slow relaxation. Whenlight falls upon the retina corresponding phenomena are to be observed. An American Text-Book of Physiology, William H. Howell, , p. 343. An Experimental Study of Sleep 83 in regard to most or to all the ordinary stimuli of the externalenvironment, the cell may be said to be fully asleep. Should however, the liberation of energy by variousstimuli keep on and begin to liberate the reserve energylevels and then pass over into the levels of static energy, thecell falls into a pathological waking state. We may represent th
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