Electron microscopy; proceedings of the Electron microscopy; proceedings of the Stockholm Conference, September, 1956 electronmicrosco00euro Year: 1957 The Importance of an Accurate Size Determination of Fine Particles when Investigating Their Biological Effects G. Bloom, J. Glomme and A. Swensson Department of Occupational Medicine, Karolinska sjiikhiiset; King Gitstaf V Research Institute and the Department of Histology, Karolinska Institiitet. Stockholm When studying the biological reactions to different particles it has become evident that the size of the latter is of importance. With the
Electron microscopy; proceedings of the Electron microscopy; proceedings of the Stockholm Conference, September, 1956 electronmicrosco00euro Year: 1957 The Importance of an Accurate Size Determination of Fine Particles when Investigating Their Biological Effects G. Bloom, J. Glomme and A. Swensson Department of Occupational Medicine, Karolinska sjiikhiiset; King Gitstaf V Research Institute and the Department of Histology, Karolinska Institiitet. Stockholm When studying the biological reactions to different particles it has become evident that the size of the latter is of importance. With the aid of the micro- scope it is possible to obtain a particle size distribu- tion of a given sample, but this method is naturally limited by the resolving power of the microscope used. As the biologically most active particles often are of such a size that a closer examination of them is not possible in the ordinary light microscope, indirect methods have been used to determine their 100%%%%%%%%%%%%%%%% 80 60 P:1 TOXICITY 1,110,06 EXCRETION 6,55%%%%%%%%%%%%%%%% 40 A = 0,I5/J 20 0 4^- 02 ^ 00%%%%%%%%%%%%%%%% P:2 80 TOXICITY 1,8 i 60 EXCRETION — 4U A=0,40ju 20 ^ 0 t'JMV^^^ I00%%%%%%%%%%%%%%%%| 80 60 40 20 0 Q2 Q6 0,8 1,0 ^ P--3 TOXICITY * EXCRETION %%%%%%%%%%%%%%%% A =^ 04 06
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