mRNA ebola vaccine, illustration. This vaccine uses replicon mRNA (messenger ribonucleic acid), a self-replicating nucleic acid, to prime a recipient'
mRNA ebola vaccine, illustration. This vaccine uses replicon mRNA (messenger ribonucleic acid), a self-replicating nucleic acid, to prime a recipient's immune system. mRNA (yellow) that encodes ebola virus glycoprotein is extracted from an ebola virus (left) and packaged in a dendrimer nanoparticle (blue). The dendrimer protects the mRNA from degradation when injected into the host and helps with delivery to a host cell. Once inside the host cell the mRNA produces ebola virus glycoproteins, which are displayed in the host cell's membrane. The expression of this foreign antigen activates the body's immune system (red cells) to produce antibodies against the antigen that protect against future infections with the actual virus (far right).
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Photo credit: © MIKKEL JUUL JENSEN/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No
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