Brain surgery . ound cells crowded in the pericellular space; the cell y shows aseries of liquefying seams or channels. at one margin of the cell body. These vesicles fre-quently appear at the junction of one of the largerprocesses with the cell body as in Fig. 28, x, Fig. 29,a, or in the process itself some little distance from thecell (Fig. 29, a). In a somewhat later stage, by the increase of thesevesicles, and by their apparent coalescence, the cellbody becomes more reduced in volume, deformed inits contours, and loses its processes. Besides the vesi-cles, liquefied seams and communicating
Brain surgery . ound cells crowded in the pericellular space; the cell y shows aseries of liquefying seams or channels. at one margin of the cell body. These vesicles fre-quently appear at the junction of one of the largerprocesses with the cell body as in Fig. 28, x, Fig. 29,a, or in the process itself some little distance from thecell (Fig. 29, a). In a somewhat later stage, by the increase of thesevesicles, and by their apparent coalescence, the cellbody becomes more reduced in volume, deformed inits contours, and loses its processes. Besides the vesi-cles, liquefied seams and communicating channels also 90 BRAIN SURGERY. appear and contribute their share toward the destruc-tion of the cells. A very beautiful example of these channels or seamsis shown in Fig. 28, y. This is one of the very largeganglion cells peculiar to the deeper layers of themotor zone and it was situated on the extreme edge ofthe section, so that it must have been immediatelyfixed by the hardening solution, and may be regarded. Fig. 29.—Other Variations of the Phases of Degeneration of the Ganglion Cellsdescribed in Figs. 27 and 28. therefore as showing very nearly the same conditionpossessed during life. The cell c, Fig. 29, also shows a somewhat similarcondition and illustrates how the apical process isbeing separated from the cell; the protoplasm sur-rounds the nucleus as a deformed or deficient masssuch as is shown in Fig. 27, w and s, and Fig. 29, b. In some of the degenerated cells the protoplasm atthe bounding surface becomes frayed out, or loosenedfrom the cell body in little granular islands or cord- TREPHINING FOR EPILEPSY. 91 like masses, while the remainder of the cell body maybe comparatively intact. This is represented in , u, and in Fig. 29, a. The cell a, Fig. 29, is againone of the very large cells in the deeper layers andwas situated just at the free edge of the section sothat it must have been fixed in a perfectly naturalcondition. In still others of the ganglion ce
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