. Electron microscopy; proceedings of the Stockholm Conference, September, 1956. Electron microscopy. Studies on the Fibrogenesis of Collagen Sylvia Fitton Jackson Medical Research Council Biophysics Research Unit, Wheatsioiie Laboratory, King's College, London, Collagen protein is widely distributed in the various phyla of the animal kingdom (3; Rudall, 1955). Recognition of its presence may be based in the characteristic fibre diagrams obtained from va- rious materials by means of high angle x-ray ditlYac- tion. Though different sources of collagen give fibre diagrams indicating substa
. Electron microscopy; proceedings of the Stockholm Conference, September, 1956. Electron microscopy. Studies on the Fibrogenesis of Collagen Sylvia Fitton Jackson Medical Research Council Biophysics Research Unit, Wheatsioiie Laboratory, King's College, London, Collagen protein is widely distributed in the various phyla of the animal kingdom (3; Rudall, 1955). Recognition of its presence may be based in the characteristic fibre diagrams obtained from va- rious materials by means of high angle x-ray ditlYac- tion. Though different sources of collagen give fibre diagrams indicating substantial differences of orien- tation and crystallinity. they are all recognizably belonging to the same class of protein. On the other hand, there are variations, for instance, in the amino- acid composition and in the structure of the con- stituent fibrils as seen by means of electron micros- copy. It is of interest, therefore, that though a typical fibre diagram for collagen is obtained from the cuticle of annelids (I), the characteristic axial perio- dicity of about 640 A of the fibrils is apparently lacking (4). It was thought that an investigation of the fine structure of the cuticle of the annelid, Liimbricus sp., by the use of thin sections in the electron microscope might help to elucidate the. Fig. 1. Section through the ctiticlc of Liiinhriciis sp. whicli shows the layers of fibrils which lie adjacent to the epidermal cells. Cytoplasmic processes stretch between the cell surface and the outer membrane of the worm, and form a basket- weave pattern with the fibrils. The microvilli on the outer surface of the worm are seen at the top of the micrograph. Magnification 23,000. method whereby the protein molecules became orien- tated into the distinctive layered structure which has been shown to be a feature of this material. This work is still in a preliminary stage, but it has been found that the cuticle is composed of five regions. The region adjacent to the main body of th
Size: 1459px × 1712px
Photo credit: © The Book Worm / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookcollectionbiodiversity, bookleafnumber245
