. Pathogenic microörganisms; a practical manual for students, physicians, and health officers . centsangina and noma and act as a contributing factor in other lesions. The fusiform baciUi are anaerobic and have been cultivated. The most BACILLUS TYPHI-EXANTHEMATICI 451 successful methods of isolation and cultivation are those of Xrumwiedeand Pratt who studied fifteen strains from various conditions. Thetypical bacillus is double-pointed, containing one or more granules. Inculture the morphology is \ariable. In fluid media there is a tendencyto produce filamentous types, which may form tangled
. Pathogenic microörganisms; a practical manual for students, physicians, and health officers . centsangina and noma and act as a contributing factor in other lesions. The fusiform baciUi are anaerobic and have been cultivated. The most BACILLUS TYPHI-EXANTHEMATICI 451 successful methods of isolation and cultivation are those of Xrumwiedeand Pratt who studied fifteen strains from various conditions. Thetypical bacillus is double-pointed, containing one or more granules. Inculture the morphology is \ariable. In fluid media there is a tendencyto produce filamentous types, which may form tangled, thread-likemasses. The colonies are characterized by thread-hke outgrowths. Thefifteen cultures studied fell into saccharose fermenting and saccharosenon-fermenting groups, but this difl^^erence had no correlation to the sourceof the culture. The fusiform bacillus and the spirochetes accompanyingit in the lesion were never encountered in cultures made from singlecolonies although Tunnicliff claimed that the fusiform bacillus and thespirochete were only different forms of the same Fig. 158.—Vincents bacillus with accompanying spirochetes. BACILLUS TYPHI-EXANTHEMATICL Historical.—The bacillus typhi-exanthematici was first isolated byPlotz, in 1914, fjom the blood of individuals suffering from typhus year later, Plotz, Olitsky and Baehr published the report of an exten-sive study of bacteriological, serological and animal investigations whichcontained much evidence that this organism is the causative agent intyphus fever. Continued investigations by these workers and by othersworking in cooperation with them have made the evidence following description is from their reports and from a private com-munication from Dr. Baehr, giving information of work to be reportedin the Journal of Infectious Diseases early in 1917. Morphology.—^The organism is a small, slender bacillus, the averagelength being about one micron. In young cultures the organis
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