. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. 320 Suppuration spheric or elongate (lemon shaped), finely granular, and lobulated like a raspberry or mulberry. When superficial they are white and elevated, i to 2 mm. in diameter. Gelatin.—In gelatin punctures a large white surface growth takes place, but development in the puncture is very scant, the small spheric colonies usually remaining isolated. The gelatin is not liquefied. Agar-agar.—Upon agar-agar spheric white colonies are produced. They may
. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. 320 Suppuration spheric or elongate (lemon shaped), finely granular, and lobulated like a raspberry or mulberry. When superficial they are white and elevated, i to 2 mm. in diameter. Gelatin.—In gelatin punctures a large white surface growth takes place, but development in the puncture is very scant, the small spheric colonies usually remaining isolated. The gelatin is not liquefied. Agar-agar.—Upon agar-agar spheric white colonies are produced. They may remain discrete or become confluent. Potato.—Upon potato a luxuriant, thick, white growth is formed. Blood-serum.—The growth upon blood-serum is also abundant, especially, at the temperature of the incubator. It has no distinctive Fig. 113.—Micrococcus tetragenus; colony twenty-four hours old upon the surface of an agar-agar plate. X 100 (Heim). Pathogenesis.—The introduction of tuberculous sputum or of a minute quantity of a pure culture of this coccus into white mice usually causes a fatal bacteremia in which these organisms are found in small numbers in the heart's blood, but are numerous in the spleen, lungs, liver, and kidneys. Japanese mice and white mice are highly susceptible to the organism and die three or four days after inoculation. House-mice, field-mice, and rabbits are comparatively immune. Guinea-pigs may die of general septic infection, though local ab- scesses result from subcutaneous inoculation. The tetracocci, when present, probably hasten the tissue-necrosis in tuberculous cavities, aid in the formation of abscesses of the lung and contribute to the production of the hectic fever. An interesting contribution to the relationship of this coccus to human pathology has been made by Lartigau,* who succeeded in demonstrating that the tetracoccus may be the cause of a pseudo- membranous angina, 3 cases of which came under his observat
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbacteri, bookyear1916
