Microtubules, 3D computer artwork. Microtubules are polymers of the protein tubulin. They are a component of the cytoskeleton, which maintains a cell'
Microtubules, 3D computer artwork. Microtubules are polymers of the protein tubulin. They are a component of the cytoskeleton, which maintains a cell's shape, allows some cellular mobility and is involved in intracellular tubular polymers of tubulin can grow as long 50 micrometres and are highly dynamic. In Alzheimer's disease, the transport of tau-protein (belonging to the MAP proteins) stabilizing the microtubules is disturbed and allows phosphate-groups to attach to the tau-protein, destabilizing the microtubuli of brain axons. This leads to the agglutination of the nerve cells resulting in neuronal degeneration.
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Photo credit: © ALFRED PASIEKA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
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