Archives of internal medicine . Diphtheria and interstitial euit hit- streptococcus and staphylococcus. Only tissue of the kidnej wasavailable. In the kidney uric marked arterial lesions of this acute type. From a Btudy of these cases it ia evidenl thai marked arterial lesionsof this type, although nol common, do occur with moderate frequency,and are pretty well distributed throughoul the different organs. They CHANNING FROTHI\<!HAM. JR. 105 seem to occur chiefly in infections caused by or complicated with the pus-forming cocci. In no case could the possibility of the bact
Archives of internal medicine . Diphtheria and interstitial euit hit- streptococcus and staphylococcus. Only tissue of the kidnej wasavailable. In the kidney uric marked arterial lesions of this acute type. From a Btudy of these cases it ia evidenl thai marked arterial lesionsof this type, although nol common, do occur with moderate frequency,and are pretty well distributed throughoul the different organs. They CHANNING FROTHI\<!HAM. JR. 105 seem to occur chiefly in infections caused by or complicated with the pus-forming cocci. In no case could the possibility of the bacteria beingpresent in the lesion be excluded, although they were not case of periarteritis nodosa reported by Longcope2 shows a similarlesion and is considered to be due to some infectious process. KecentlyMallory3 has found similar lesions in the arteries of the heart duringacute articular rheumatism. The end-result of such a lesion on healingmust show a permanent scar in the arterial wall. Jt seems reasonable. Marked arterial lesion found in an artery in the kidney following scarlet fever. to suppose that less severe infections of the same type which terminatein recovery may cause similar arterial lesions with an arterial scar carriedinto later life. The question immediately arises. Do repeated lesions ofthis sort lead to the so-called arteriosclerosis of old age? If such alesion heals with a partial occlusion of the lumen, it is reasonable to 2. Longcope: Bull. Aver Clin. Lab., Fenn. Hosp., December, 1908. 3. Mallory, F. B.: Unpublished article. in., THE IRCHIVE8 OF INTERNAL MEDICINE suppose that the vessel wall distal to this poinl ma\ suffer from dimin-ished blood-supply. It is also possible that the arterial wall adjaceni tothe scar may suffer from lack of nutrition due to the surrounding scartissue. With the hope thai clinical histories mighi throw some light on thecause of arteriosclerosis the record of two patients with marked sclerosisof the arteries a
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