. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. ii8 Immunity An analysis of tliis theory shows complete natural immunity to depend upon the absence of haptophore groups (receptors) by which the toxins can be united to the cells. Extreme sensitivity or susceptibility probably depends upon the adapted haptophores being present or at least most numerous upon the cells of highly vital organs; comparative insensitivity or insusceptibility upon the fact that the greater number of haptophore groups are attac
. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. ii8 Immunity An analysis of tliis theory shows complete natural immunity to depend upon the absence of haptophore groups (receptors) by which the toxins can be united to the cells. Extreme sensitivity or susceptibility probably depends upon the adapted haptophores being present or at least most numerous upon the cells of highly vital organs; comparative insensitivity or insusceptibility upon the fact that the greater number of haptophore groups are attached to comparatively unimportant cells whose combining affinities have to be satisfied before combination with more vital cells can be accomplished. In some cases natural immunity is increased by the presence of free haptophore groups (antitoxin) in the blood. Acquired immunity against toxins depends upon the regeneration of the cellular hapto- phores or receptors which, being liberated into the body juices, fix the haptophores of the toxin molecules before they are able to reach the cells themselves. Antitoxins and other anti-bodies, including the lysins, consist of liberated cellular haptophores or receptors, the former having a single combining affinity, the latter a double combining affinity, by which they unite, on the one hand, with the Fig. ^ ^ ^^ dissolved, on the other with the ceptors of the second ..... i i- i j order (a) by which the complement by which it IS to be dissolved, cells fix useful molecules, Antibodies having this double combining hin'd'cS'andVmog^: affinity have been called "amboceptors" by molecules (c) on the other Ehrlich. They are variously known in dif- hand, and make use of the fgrent writings as "immune bodies," ambo- one substance through , , , ., .,. ^ . , , the action of the other. ceptors, substance sensibiksatrice, desmon, and fixateur. The "complement" or "addi- ment" of Ehrlich is als
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbacteri, bookyear1916
