. A practical treatise on diseases of the skin, for the use of students and practitioners. rarely freely exfoliating. They are relatively few,occurring where the lesions are closely set together. The desquamationmay be the most suggestive feature of the patch. Beneath the scalesare seen distinctly elevated brownish-red papules or merely slightlyelevated, dull-red or purplish-red maculations. When the scales accum-ulate at the base of the papule they tend to surround it with a circletor collarette of exfoliated shreds of epidermis. 1 Annal. Clin, de Osped. Incurab. 616 DISEASES OF THE SKIN. In


. A practical treatise on diseases of the skin, for the use of students and practitioners. rarely freely exfoliating. They are relatively few,occurring where the lesions are closely set together. The desquamationmay be the most suggestive feature of the patch. Beneath the scalesare seen distinctly elevated brownish-red papules or merely slightlyelevated, dull-red or purplish-red maculations. When the scales accum-ulate at the base of the papule they tend to surround it with a circletor collarette of exfoliated shreds of epidermis. 1 Annal. Clin, de Osped. Incurab. 616 DISEASES OF THE SKIN. In consequence of the thickness of the epidermis in the palms andsoles, the papular or papulo-squamous syphiloderm of these regions ispresented under somewhat atypical forms, which are recognized as thePalmar and the Plantar Syphilides. The dense stratum corneumof the epidermis in the palms and soles is not readily raised from itsunderlying tissue into papular forms. The pathological manifestationsof this disease are rather displayed in thickenings, separations, stain-ings, and Palmar syphiloderm (after Keyes). Here, therefore, are seen dull-red maculations, covered throughout?or merely at the edges, by scales or epidermal shreds; minute, firm,corneous thickenings, few or many, often without color in consequenceof the depth of the blood-vessels beneath the opaque horny layer; anddistinctly elevated (not flattened) and circumscribed papules, of theusual livid-red color, coffee-bean- to small-nut-sized, often aggregatedin patches having a tendency to assume the circinate outline. Occasion-ally pin-head-sized and larger deposits resembling chalk may be pickedwith a pointed instrument from circular beds in the palms and soleswhere the lesions first developed. These and similar spots may becovered with dirty-whitish, tenacious, half-loosened, epidermic flakes,which are quite characteristic. In other cases, usually in consequenceof the motions of the hand or the foot or the e


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Keywords: ., bookauthorhydejamesnevins184019, bookcentury1800, bookdecade1890