Medical and surgical report of the Presbyterian Hospital in the City of New York . es broken up in salt swellings were produced at the point of inoculation and anumber of abscesses resulted. The abscesses developed rapidly andsome of them opened spontaneously, while others were incised. Thematerial evacuated did not resemble ordinary pus, but was thick andmucilaginous and exceedingly tenacious, like that from the subcu-taneous abscesses of the patient as described above. The microscop-ical appearance was the same, and the streptothrix threads were foundin considerable number
Medical and surgical report of the Presbyterian Hospital in the City of New York . es broken up in salt swellings were produced at the point of inoculation and anumber of abscesses resulted. The abscesses developed rapidly andsome of them opened spontaneously, while others were incised. Thematerial evacuated did not resemble ordinary pus, but was thick andmucilaginous and exceedingly tenacious, like that from the subcu-taneous abscesses of the patient as described above. The microscop-ical appearance was the same, and the streptothrix threads were foundin considerable numbers. Pure cultures of the streptothrix were easilyobtained from the pus whether the abscesses ruptured spontaneouslyor were incised. Indeed, in all of the inoculation experiments it was STREPTOTHRIX INFECTION. l6l very rare that the cultures showed any other micro-organism besidesthe streptothrix. Not a single instance of mixed infection the evacuation of the abscesses, either by rupture or by incision,the surrounding induration gradually disappeared and the ulcers. Fig. 6.—Streptothrix in lung, highly magnified. Original case healed. In many cases the induration did not result in abscess butgradually resolved. The animals showed no signs of illness and noneof them developed a general infection or died. Several rabbits andguinea-pigs and two cats received peritoneal inoculations, but none l62 STREPTOTHRIX INFECTION. of them showed any sign of infection. Sometimes at the point of inocu-lation a few tubercular nodules were found at autopsy, but cultureswere not obtained from them. No local infection of anv consequenceand no general infection was produced in this way. Thus far littlevirulence had been shown by the streptothrix in inoculation when rabbits were inoculated intravenously, a rapidly fatal generalinfection was produced, and the lesions were similar in kind and dis-tribution to those described in the human subject. A description ofone of th
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