A treatise on the nervous diseases of children, for physicians and students . nearlyof normal size, increase of the interstitial connective tissue, no hyper-trophied fibres, and strands of connective tissue occasionally passingthrough the fatty parts ; a few of the groups of muscle fibres appearingto be strangulated by the strands of connective tissue. In sections froma case which I have recently had occasion to examine, the fibres were foundto be of varying size and there was a distinct proliferation of the musclenuclei. Schultze, in a case which stands midway between pseudo-hyper-trophy and
A treatise on the nervous diseases of children, for physicians and students . nearlyof normal size, increase of the interstitial connective tissue, no hyper-trophied fibres, and strands of connective tissue occasionally passingthrough the fatty parts ; a few of the groups of muscle fibres appearingto be strangulated by the strands of connective tissue. In sections froma case which I have recently had occasion to examine, the fibres were foundto be of varying size and there was a distinct proliferation of the musclenuclei. Schultze, in a case which stands midway between pseudo-hyper-trophy and Erbs juvenile form, found, in addition to peculiar giant-cell for-mations, a large number of fat-cells in the muscular tissue, an increase of theconnective tissue, and remnants of hypertrophied, normal, and atrophic fibres,and an enormous increase of nuclei, which the author thought greater thanin the ordinary cases of pseudo-hypertrophy. He also described the occur-rence of vacuoles which were in all probability not due to the hardening PROGRESSIVE MUSCULAR ATROPHIES. 433. lis J*? rr--i Fig. hi.—Chnnges in Muscular Tissue in a Caseof Primary Dystrophy. (Erb.) a, Above alteredblood-vessel; for other lettering see text. process. Hitzigs observations were of special interest for a time, as heexamined four cases most carefully. He concluded that the primary andmost important change in juvenile atrophy is not an interstitial process, butdecidedly parenchymatous, and according to the intensity of the disease isrepresented by slight or ex-cessive hypertrophy of thefibres . . The anatom-ical changes in pseudo-hyper-trophy, on the other hand,are characterized by activechanges in the connectivetissue. This distinction be-tween the histological changesin pseudo - hypertrophy andErbs form of primary myop-athy has not been borne outby others, and if I am notmistaken, Hitzig has with-drawn his former views. The matter was definitely settled by more recentand extremely thorough studies of
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectnervous, bookyear1895
