Transactions of the Royal Society of Edinburgh . did not think it necessary to perform another experiment, for the firstexperiment with this substance may be regarded as sufficient. Table XXII.—Composition of the Bile before and after Colocynth. Experiment 39. Before. After. - Bile-acids, pigments, cholesterin, fats, .... Mucus, Ash, 92-995-490-900-62 94-134-700-700-47 100-00 100-00 Velocity of secretion per half hour, ..... 3-4 cc. 6-35 cc. The analysis shows that colocynth renders the bile more watery, but it isevident from the increased velocity of secretion that it compels the liver tosecr
Transactions of the Royal Society of Edinburgh . did not think it necessary to perform another experiment, for the firstexperiment with this substance may be regarded as sufficient. Table XXII.—Composition of the Bile before and after Colocynth. Experiment 39. Before. After. - Bile-acids, pigments, cholesterin, fats, .... Mucus, Ash, 92-995-490-900-62 94-134-700-700-47 100-00 100-00 Velocity of secretion per half hour, ..... 3-4 cc. 6-35 cc. The analysis shows that colocynth renders the bile more watery, but it isevident from the increased velocity of secretion that it compels the liver tosecrete more of the biliary solids proper. Results of Experiments with Colocynth.—Colocynth is, in large doses, apowerful hepatic, as well as intestinal stimulant. Though rendering the bilemore watery, it increases the secretion of biliary matter. 188 PROFESSOR RUTHERFORD ON THE Action of Jalap. What is known of the action of jalap on the liver has been already referredto under colocynth. The maximum dose of jalap powder for a man is 30 Fig. 41.—Secretion of bile before and after jalap. 2 5 and 25 cc. water injected into the duodenum at grains of jalap powder in the same fluid Experiment 41. Dog that had fasted seventeen hours. Weight 25 kilo-grammes (fig. 41).—25 cc. bile and -2*5 cc. water injected into the duodenum Experiment 41. Secretion Secretion Secretion of bile per Secretion of bile per of bile per kilogramme of bile per kilogramme 15. of dog : per 15. of dog: per hour. hour. cc. cc. 1-1 1-6 1-1 1-5 1-0 1-65 1-0 1-4 b ? 1-8 0-95 1-9 1-0 ) 1-9 \ 1-05 ^0-16cc. 1-8 1 1-0 ! 1-9 > 0-296 cc. 1 i 1-8 ) 1-0 1-6 1-1 1-2 1-15 1-4 1-4 1-1 1-45 ! at b. 30 grains of jalap powder in the same fluid injected at/. Table XXIII. Jalap. Total Dose in Grains. Grains per Kilogrammeof Body-weight. Secretion of ,gramme ofper Before. Jile per Kilo- Body-weight lour. After. Experiment 41,42 30 with bile,40 1-23-2 0-16 cc. 0-29 cc. Table
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