. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. RADIATION OF CELLULAR PARTICULATES 201 TABLE II The effect of aging on the inactivation of cytochrome oxidase Morning Afternoon Y\ No. runs Per cent inactivation No. runs Per cent inactivation 5,000 4 ± 4 ± 15,000 4 ± 4 ± 20,000 4 ± 4 ± which the number of mitochondria in each sample are the same, no conclusions can be drawn about the variability between rats. The data in Table I indicate that the preparations become more sensitive to low doses of radiation with time. On the first day,
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. RADIATION OF CELLULAR PARTICULATES 201 TABLE II The effect of aging on the inactivation of cytochrome oxidase Morning Afternoon Y\ No. runs Per cent inactivation No. runs Per cent inactivation 5,000 4 ± 4 ± 15,000 4 ± 4 ± 20,000 4 ± 4 ± which the number of mitochondria in each sample are the same, no conclusions can be drawn about the variability between rats. The data in Table I indicate that the preparations become more sensitive to low doses of radiation with time. On the first day, a dose of 2500 r produces little or no inactivation; on the second day, it produces about 6 per cent. This is shown in a much more striking manner in Table II. In this case the data from some runs done on the first day are broken down into those done in the morning and those done in the afternoon. In all cases, a preparation was radiated in the morning and afternoon, the only difference being the age. It is evident that when the mito- chondria are first extracted they are much more resistant to radiation, particularly at the lower doses. At high doses, Table I indicates that there is a progressive decrease in sensitivity with age. Intermediate doses are erratic. As a result of 50 40 20 10. 40 FIGURE 1. Inactivation of cytochrome oxidase by gamma radiation. Points represent means, with standard errors shown as limits. Preparation radiated the same day it was ex- tracted. The dotted line represents the best fit of a regular Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983
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