A manual of venereal diseases . been made by Krzystalowicz andSiedlecki ^ who describe true longitudinal division,an indication of an undulating membrane as wellas a nucleus and centrosome. They also figure aflagellum, of a different nature to that just described,which starts from the neighbourhood of the centro-some and courses down the body of the parasitefor a short distance, but does not project beyond itsextremity. They further note the existence of shortand comparatively thick parasites, in which theabove details of structure are most evident, andthey suggest that a process of conjugatio


A manual of venereal diseases . been made by Krzystalowicz andSiedlecki ^ who describe true longitudinal division,an indication of an undulating membrane as wellas a nucleus and centrosome. They also figure aflagellum, of a different nature to that just described,which starts from the neighbourhood of the centro-some and courses down the body of the parasitefor a short distance, but does not project beyond itsextremity. They further note the existence of shortand comparatively thick parasites, in which theabove details of structure are most evident, andthey suggest that a process of conjugation occursbetween individuals of different sexes. They con-clude, as a result of their observations, that theparasite is, without doubt, a trypanosome. Theseremarkable observations are, as yet, un-confirmedand, from the extremely minute size of the organism,it is obvious that the interpretation of the finerdetails of structure is as difficult a task as could wellbe imagined. A possible s^^^^ of confusion, aii^i^at the same MAR 2. r T nt SYPHILIS : PATHOLOGY 51 time, a possible solution of the difficulty, lies inthe existence of the parasitic bodies found by Siegel ^in syphilitic material and thought by him to bethe cause of the disease. To these bodies he hasgiven the name of Cytorrhyctes luis and he con-siders them to be of the same Genus as those whichhe has found in Smallpox, Foot and Mouth Diseaseand Scarlet Fever. This Cytorrhyctes, accordingto Siegel, follows a complicated cycle of develop-ment, which need not be described here, and someof the forms may, as has been suggested, representstages in the development of Spirochaeta little or no support has been accordedto the Cytorrhyctes luis as being the causativeagent of syphilis, there appears little doubt thatthese bodies are at times to be found in syphiHticmaterial and the part which they play, if any, inthe disease is one of the many points on whichwe must await further research. Negative resultsare, perh


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