The chemist and druggist [electronic resource] . RA linkedto smoking If any more incentive wasneeded to quit smoking, theresults of a recent Finnish studyshould be sufficient. Over 50,000 adults who werefree of arthritis and had nohistory of the disease werefollowed up from 1966-72 to1989 by record linkage. Fivehundred cases of rheumatoidarthritis (RA) occurred, ofwhom two-thirds wereseropositive (having auto-antibodies in the blood). Seropositive RA wassignificantly correlated withsmoking in men but notwomen. Compared withlifetime non-smokers, theexcess risk was in ex-smokers and in c
The chemist and druggist [electronic resource] . RA linkedto smoking If any more incentive wasneeded to quit smoking, theresults of a recent Finnish studyshould be sufficient. Over 50,000 adults who werefree of arthritis and had nohistory of the disease werefollowed up from 1966-72 to1989 by record linkage. Fivehundred cases of rheumatoidarthritis (RA) occurred, ofwhom two-thirds wereseropositive (having auto-antibodies in the blood). Seropositive RA wassignificantly correlated withsmoking in men but notwomen. Compared withlifetime non-smokers, theexcess risk was in ex-smokers and in currentsmokers, excluding potentiallyconfounding factors. Smoking probably does notcause RA but may be a pathogenicfactor. Why this is so in men butnot women is of Rheumatology 1993;20: 1830-5 Chemist & Druggist 29 JANUARY 1994. Neuroleptics forthe acutely illelderly patient There has been concern in theUS that neuroleptics may beprescribed for elderly patientsin institutions to control theirbehaviour rather than treat amedical condition. There is nowlegislation which restricts theuse of these drugs to definedpsychiatric diagnoses amongresidents of nursing homes. Butno such controls apply toelderly patients admitted togeneral hospitals. A survey of drugs prescribedfor 848 elderly patients onmedical and surgical wards in aMassachusetts hospital foundthat 11 per cent had beenprescribed neuroleptics —principally a diagnosis ofdementia was confirmed inover half of these cases, nearlyone-third had simply beendescribed as agitated or had noapparent need for neuroleptictreatment. Despite the risks associated with this class of drugs, anassessment of mental status hadbeen recorded in fewer than 40per cent of patients. At theother extreme, special testssuch as computed tomographicscan of the hea
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Keywords: ., bookcentury1800, bookdecade185, booksubjectpharmacy, bookyear1859