The Journal of nervous and mental disease . shown in the followingtable: Boston State Hospital Optic Nerve Changes in Unselected Autopsy Cases Cases in random series, 1913 58 Cases with optic nerve changes (Weigert) (unilateral, 13 ; bilateral, 27) 40Cases with spinal cord changes (Weigert) 34 S3philitics in series 18 With optic nerve changes (unilateral, 3; bilateral, 12) ..... l%8 With spinal cord changes l%8 With optic nerve and cord ii^g Non-syphilitics in series 40 With optic nerve changes (unilateral, 10; bilateral, 15) .... 2^0 With spinal cord changes 2%0 With optic nerve and cord 1%0


The Journal of nervous and mental disease . shown in the followingtable: Boston State Hospital Optic Nerve Changes in Unselected Autopsy Cases Cases in random series, 1913 58 Cases with optic nerve changes (Weigert) (unilateral, 13 ; bilateral, 27) 40Cases with spinal cord changes (Weigert) 34 S3philitics in series 18 With optic nerve changes (unilateral, 3; bilateral, 12) ..... l%8 With spinal cord changes l%8 With optic nerve and cord ii^g Non-syphilitics in series 40 With optic nerve changes (unilateral, 10; bilateral, 15) .... 2^0 With spinal cord changes 2%0 With optic nerve and cord 1%0 40 cases with optic nerve were e5^e workers. What are the changes seen in the fifteen syphilitic opticnerves? In general, peripheral degeneration of the nerve (seeFig. i). To briefly particularize—in five cases: B. S. H. No. 9825, Path. —Female. Age 56; diag-nosis, general paresis; married twice; had two children by first,none by second husband. Had broken leg three times by falls,and had rheumatism for twenty Fig. I. Peripheral degeneration of optic nerve in a syphilitic. B. S. Weigerts myeline sheath stain. Dtiration of her mental trouble was about two years, sixmonths. She had rather suddenly become slovenly, irritable anderotic; was sent here because she wandered away and her mem- MYRTELLE M. CAXAVAN orv failed. Pupils were irregular and unequal, but reacted tolight and accommodation. Xo ophthalmoscopic examination wasmade. Wassermann reaction not done. She had absent knee jerks, speech defect, ataxia, tremors andRomberg, and her judgment was poor, and she gave evidence ofdementia. Sections of the brain show marked infiltration of vessels, dis-order and destruction of cells, and sections of the cord show agummatous meningitis; over mid-dorsal region, and posteriorcolumn sclerosis. The optic nerve shows slight peripheral lossof myelin sheaths and by Levaditi stain a spirochete, located inthe pial sheath. B. S. H. No. 9206, Path


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic