A text-book of practical therapeutics . obvious difficulties in the preparation and keepingof Dakins solution toluene sulphondichloramine, in other words,toluene dichloramine, or dichloramine-T, has been introduced as asubstitute, depending for its very high germicidal action upon thelarge amount of active chlorine which it contains. Dichloramine-T 544 REMEDIAL MEASURES OTHER THAN DRUGS appears as a yellowish white crystalline substance, when made withchloroform, possessing rather a sweet odor with some pungencyresembling chlorine. When made commercially on a large scale invacuum it appears as
A text-book of practical therapeutics . obvious difficulties in the preparation and keepingof Dakins solution toluene sulphondichloramine, in other words,toluene dichloramine, or dichloramine-T, has been introduced as asubstitute, depending for its very high germicidal action upon thelarge amount of active chlorine which it contains. Dichloramine-T 544 REMEDIAL MEASURES OTHER THAN DRUGS appears as a yellowish white crystalline substance, when made withchloroform, possessing rather a sweet odor with some pungencyresembling chlorine. When made commercially on a large scale invacuum it appears as a powder. When first employed it was usedin a strength varying from 2 to 5 per cent., the solution havingbeen made by dissolving it in a mixture of eucalyptol and paraffineoil. The use of this mixture was resorted to first because dichlora-mine-T is practically insoluble in water and the use of eucalyptolcauses the chlorine to be given off slowly over many hours insteadof all at once. Thus, while most of the chlorine may be lost from. Fig. 66.—Apparatus for applying Carrel-Dakin solution. This apparatus isfurnished by instrument dealers. A, reservoir graduated; B, clamp for regulatingflow; C, sight feed cup; D, four-way glass distributor; E, perforated distributing tubeswith ends tied. When used for surface ends are covered with Turkish toweling;F, five-way glass distributor; G, one tube glass distributor; H, two-way glass distributor;/, syringe for applying solution by hand; J, flask for use with syringe. Dakins solution in a few minutes, the oily dichloramine-T solutionlasts as many hours. The oil further acts as a protective dressingin itself and permeates all parts of the wound so that very smallquantities cover a very large area. Any irritation of the skin canbe avoided by using light dressings. Even when eucalyptol is employed the product, as already stated,soon becomes of uncertain strength. Dakin has improved uponthe eucalyptol-paraffine mixture by treating any pure
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Keywords: ., bookcentury1900, bookdecade1920, booksubjecttherape, bookyear1922
