Gall-stones and diseases of the bile-ducts . Fig. 14.—Gall-bladder of a dog opened longitudinally showingtwo gall-stones formed around a thread experimentally in-troduced (Mignot). Six weeks later the dog was again operated uponand the compress removed from the gall-bladder; atthe same time a fixed thread 2 cm. long was intro-duced into the gall-bladder wall and the free endallowed to float freely in its cavity. In June, 1898,cholecystectomy was performed on the living dogand two cholesterin calculi were found on the threadin the gall-bladder. 52 DISEASES OF THE BILE-DUCTS Mignot found that as


Gall-stones and diseases of the bile-ducts . Fig. 14.—Gall-bladder of a dog opened longitudinally showingtwo gall-stones formed around a thread experimentally in-troduced (Mignot). Six weeks later the dog was again operated uponand the compress removed from the gall-bladder; atthe same time a fixed thread 2 cm. long was intro-duced into the gall-bladder wall and the free endallowed to float freely in its cavity. In June, 1898,cholecystectomy was performed on the living dogand two cholesterin calculi were found on the threadin the gall-bladder. 52 DISEASES OF THE BILE-DUCTS Mignot found that as long as the bacteria retaintheir virulence they do not form calculi, but only asediment mixed with pus. The attenuation of the microbe is best obtainedby growing the bacteria for some months in bile towhich constantly decreasing amounts of broth areadded. When sufficiently attenuated they are no.


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Keywords: ., bookcentury1900, bookdecade1900, bookpublishernewyorkwilliamwood