Archive image from page 709 of Currents in biochemical research, 1956;. Currents in biochemical research, 1956; twenty-seven essays charting the present course of biochemical research and considering the intimate relationship of biochemistry to medicine, physiology, and biology currentsinbioche1956gree Year: 1956 ( HAROLD P. RUSCH Theory of Cancer Formation Some aspects of carcinogenesis will now be considered. Two of the conclusions concerning the nature of cancer made by the committee in 1938 were that the causes of cancer 'are mul- tiple and diverse' and that 'once malignancy is establishe
Archive image from page 709 of Currents in biochemical research, 1956;. Currents in biochemical research, 1956; twenty-seven essays charting the present course of biochemical research and considering the intimate relationship of biochemistry to medicine, physiology, and biology currentsinbioche1956gree Year: 1956 ( HAROLD P. RUSCH Theory of Cancer Formation Some aspects of carcinogenesis will now be considered. Two of the conclusions concerning the nature of cancer made by the committee in 1938 were that the causes of cancer 'are mul- tiple and diverse' and that 'once malignancy is established in a cell it becomes an automatic process. . .which is passed un- changed to the descendants.' Research during the intervening D-MECHANISM FOR CELLULAR REDUPLICATION O-MECHANISM FOR SPECIAL FUNCTIONS g;:,-C ELL-FOOD Figure 3. years has sustained this report, and, in addition, sufficient infor- mation has been accumulated to indicate that all carcinogens induce heritable cellular changes. This change is depicted in the alteration of the normal cells B, C, and D to the neoplastic cells U, V, and W as shown in Figure 3. At first glance little difference is noted between the top two rows as to the patterns in the various cells; both have the same quantity of cell food, and both possess considerable specialized function. But one crucial difference exists. A key reaction in one of the special metabolic patterns has been 688
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