Archives of internal medicine . detection by the rabbit intestine method (described below) whichwas used. It was proved, however, that there 1- a difference of less thanl :100,000,l mi the epinephrin content of blood from the vena cava at 11. Ehrmann: Arch. f. Exper. Path. u. Phartn., 1905, Iv, 12. \\ .itt. 1 and Smit: Irch. f. d. ges. Physiol., 1908, cxxiv, L9818. <•( onnoi 1, 1 exp< 1, Path. u. Phai m. 1910, Ixiii, 161. (i. H0SK1NS—0. IT. MCLURE 34i the mouths of the lumbo-adrenal veins and that from the femoral results indicate roughly that there is in the arterial bl
Archives of internal medicine . detection by the rabbit intestine method (described below) whichwas used. It was proved, however, that there 1- a difference of less thanl :100,000,l mi the epinephrin content of blood from the vena cava at 11. Ehrmann: Arch. f. Exper. Path. u. Phartn., 1905, Iv, 12. \\ .itt. 1 and Smit: Irch. f. d. ges. Physiol., 1908, cxxiv, L9818. <•( onnoi 1, 1 exp< 1, Path. u. Phai m. 1910, Ixiii, 161. (i. H0SK1NS—0. IT. MCLURE 34i the mouths of the lumbo-adrenal veins and that from the femoral results indicate roughly that there is in the arterial blood as itleaves the heart at most, less than one part of epinephrin in 200,000, unsuccessful in these attempts, we then made a number ofdirect determinations of the epinephrin content of the blood from thelumbo-adrenal veins. The blood was collected by a method that has beenused by a number of other investigators. The animals were etherized,then, while the viscera were protected by warm towels, the vena cava and. Fig. 1.—Epinephrin content of blood from adrenal veins. Segment of rabbitintestine beating in: 1. Blood from femoral vein. 2. Blood from adrenal Adrenalin 1:4,000,000. 4. Blood from adrenal vein. 5. Adrenalin 1:8,000, Adrenalin 1:0, 7. Adrenalin 1:7,000,000. 8. Blood from adrenal diluted four times. Adrenalin solutions in blood from femoral vein simi-larly diluted. aorta were ligated posterior to the renal veins; the renal veins were ligatedat the hilus of each kidney. Then an oiled right angle glass cannula wasinserted into one renal vein so as to drain the vena cava, which wasfinally occluded by a hemostat anterior to the mouths of the lumbo-adrenal veins. Care was taken to avoid massaoino- the adrenal glands. 348 i ////1\ i:s hi i \ 11 i:\ i/. 1//:/>/< / \ /. The blood that had collected during tin- final stages of the procedure wascarefully pressed oul through tin- cannula, which was then elevated a fewcentimete
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