Nervous and mental diseases . Fig. 181.—Section of cords in advanced tabes. 1, Dorsal region ; 2, cervical region. Sclerosis shown by white region (Marie). present a marked difference between the anterior or motor members,which are ordinarily normal, and the posterior sensory roots, which areusually, if not invariably, greatly degenerated. Only when changeshave taken place in the anterior cornual cells do we find changes in theanterior roots, and then there is corresponding amyotrophy. This is 426 DISEASES OF THE CORD Fig. 182.—Section in lower dorsalcord in a case of advanced tabes s
Nervous and mental diseases . Fig. 181.—Section of cords in advanced tabes. 1, Dorsal region ; 2, cervical region. Sclerosis shown by white region (Marie). present a marked difference between the anterior or motor members,which are ordinarily normal, and the posterior sensory roots, which areusually, if not invariably, greatly degenerated. Only when changeshave taken place in the anterior cornual cells do we find changes in theanterior roots, and then there is corresponding amyotrophy. This is 426 DISEASES OF THE CORD Fig. 182.—Section in lower dorsalcord in a case of advanced tabes show-ing complete sclerosis of the posteriorcolumns and of Clarkes cellular columns(Marie). usually a late and secondary or accidental feature in tabes. The posterior roots and their ganglia show much disease. Oppenheim, Simmerling, Marie, Obersteiner,1 Juliusberger andMeyer,2 describe changes in the root-ganglion cells, which are found reducedin size and number. Nuclear displace-ment and granular changes were de-monstrated by MssPs method, accord-ing to the last-mentioned authors. Thefibers within the ganglia were alsoatrophic. The posterior roots are prac-tically always degenerated. The poste-rior root-ganglion occupies, therefore, aprominent position in the development oftabetic lesions, as it exercises a trophiccontrol, both downward over the sensory fibers of the nerves and upward over the posterior root-fibers and their continuation within the posterior tracts of the cord. Changes in the visceral branches of the
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