. Cell heredity. Cytogenetics. Control No prototrophs Prototrophic met '*' bio "*â thr â *" leu '*' From exchange mef*" bio'*' thr~ leu~ met~ bio~\thr'*' leu "*" Test for unselected markers by streaking on indicator agar Control No prototrophs / Tl \ d D [I 1 1 ID c ). Parents Prototrophic progeny FIGURE The result of plating a mixture of thr leu and met auxotrophic E. coli on agar devoid of the required growth factors (after Lederberg, 1947, Genetics, 32:505). structed in which the distances are roughly additive. The frequency of triple exchanges expected (
. Cell heredity. Cytogenetics. Control No prototrophs Prototrophic met '*' bio "*â thr â *" leu '*' From exchange mef*" bio'*' thr~ leu~ met~ bio~\thr'*' leu "*" Test for unselected markers by streaking on indicator agar Control No prototrophs / Tl \ d D [I 1 1 ID c ). Parents Prototrophic progeny FIGURE The result of plating a mixture of thr leu and met auxotrophic E. coli on agar devoid of the required growth factors (after Lederberg, 1947, Genetics, 32:505). structed in which the distances are roughly additive. The frequency of triple exchanges expected ( x X = ) is almost the same as that observed (). Even numbers of exchanges within this region would not, of course, be selected by the method used. A similar order of genes is observed by a completely different tech-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Sager, Ruth; Ryan, Francis J. (Francis Joseph), 1916-. New York, Wiley
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