. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954. Electrophysiology; Electrolytes; Electrolytes; Electrophysiology; Physiology, Comparative. ERNST G. HUF 213 ary rise. Epinephrine seems to stimulate the mucous glands of the skin (40, 70). AfterappHcation of neurohypophyseal principles, which increases net uptake of water from the outside, a higher skin potential is obtained at a given rate of sodium intlux. It has been concluded that, after the addition of the hormone, more
. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954. Electrophysiology; Electrolytes; Electrolytes; Electrophysiology; Physiology, Comparative. ERNST G. HUF 213 ary rise. Epinephrine seems to stimulate the mucous glands of the skin (40, 70). AfterappHcation of neurohypophyseal principles, which increases net uptake of water from the outside, a higher skin potential is obtained at a given rate of sodium intlux. It has been concluded that, after the addition of the hormone, more of the work done by the skin appears to be available for the formation of the potential (8). Pretreatment of frogs, before using their skins, with a highly puritied ACTH preparation changes the conditions in skin such that, for a given skin voltage, less sodium chloride is taken up by the skin of treated frogs than of untreated or sham-treated animals (28). No demonstrable difference in active salt transport seems to exist between skin of normal and of adrenohypo- physectomized frogs (^3)- mV \ / 14,3 mV Fig. 5. Development of skin po- tentials in two symmetrical pieces of skin of the abdominal wall of Rana esculenla. Frog was poisoned previous to the decapitation for 15 min. with bromoacetate ( ml of a 4% ) into the dor- sal lymph sac. la: skin immedi- ately exposed to Ringer's contain- ing I m/1. lactate. lb: skin tirst exposed to Ringer's containing m/1. glucose, later to Ringer's- lactate solution (15).. 120 150 Increasing the outside concentration of sodium chloride leads to increase of both intlux and outflux of sodium (70). The former, however, is increased more than the latter, which is to say that net salt accumulation increases upon raising the outside XaCl concentration. On the other hand, steeper gradients for NaCl are generated by skin in diluted as compared to skin in normal or more concen- trated Ringer's (24; fig. 6). The pH of the o
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