. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. Lesions 747 ing injuries to occur without detection and to progress without observation. The ulcerations of the hands and feet, with frequent loss of fingers and toes, follow these lesions, probably in the same manner as in syringomyelia. The disease usually first manifests itself upon the face, extensor surfaces, elbows, and knees, and for a long time confines itself to the skin. Ultimately it sometimes invades the lymphatics and ex- tends to the intern


. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. Lesions 747 ing injuries to occur without detection and to progress without observation. The ulcerations of the hands and feet, with frequent loss of fingers and toes, follow these lesions, probably in the same manner as in syringomyelia. The disease usually first manifests itself upon the face, extensor surfaces, elbows, and knees, and for a long time confines itself to the skin. Ultimately it sometimes invades the lymphatics and ex- tends to the internal viscera. Death ultimately occurs from ex- haustion,^ if not from the frequent intercurrent affections, especially pneumonia and tuberculosis, to which the patients seem predisposed. Specific Therapy.—Carrasquilla's* "leprosy serum" was pre. Fig. 291.—Lepra ansesthedca (McConnell). pared by injecting the serum separated from blood withdrawn from lepers, into horses, mules, and asses, and, after a number of in- jections, bleeding the animals and separating the serum. There is no reason for thinking that such a product could have therapeutic value. In practice it proved worthless. Rostf prepared massive cultures of the lepra bacillus, filtered them through porcelain, concentrated the filtrate to one-tenth of its volume, and mixed the filtrate with an of glycerin. The resulting preparation was called leprolin and was supposed to be * "Wiener med. Wochenschrift," No. 41, 1897. t "Brit. Med. Jour.," Feb. 11, Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original McFarland, Joseph, 1868-. Philadelphia and London, W. B. Saunders Company


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbacteri, bookyear1919