. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954. Electrophysiology; Electrolytes; Electrolytes; Electrophysiology; Physiology, Comparative. HUMAN SICKLE CELL ANEMIA CELLS - 37°C. Fig. 2 (left). K influx into normal human red cells exposed to m/1. n-butanol is plotted as a function of K concentration in the medium ([K]m). Fig. 3 {rigid). K influx into the red cells of a patient with sickle cell anemia incubated in O2 (disk shape) and N2 (sickle shape) is plotted as a fu
. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954. Electrophysiology; Electrolytes; Electrolytes; Electrophysiology; Physiology, Comparative. HUMAN SICKLE CELL ANEMIA CELLS - 37°C. Fig. 2 (left). K influx into normal human red cells exposed to m/1. n-butanol is plotted as a function of K concentration in the medium ([K]m). Fig. 3 {rigid). K influx into the red cells of a patient with sickle cell anemia incubated in O2 (disk shape) and N2 (sickle shape) is plotted as a function of K concentration in the medium ([K]m). The value of D'k derived from the slope of this curve is which agrees fairly well with the value obtained from the flux ratio analysis. Competition between K and Cs. In the presence of m/1. n-butanol, there is no competition between K and Cs for entrance into the human red cell. These measurements are consistent with the conclusion that K transport in human red cells exposed to m/1. n-butanol is almost entirely by the process of diffusion. Red Cells of Patients With Sickle Cell Anemia. Cation transport in sickle cell anemia (S-S) red cells has recently been characterized in detail (106, 107, 109, no, 112). When incubated in oxygen, S-S red cells remain in the disk shape and transport cations in essentially the same manner as do normal red cells. Incubation in nitrogen produces transformation from disk to sickle and marked changes in cation transport. For comoarison with normal and butanol-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Shanes, Abraham M. (Abraham Morris), 1917-; Society of General Physiologists. Washington, American Physiological Society
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