. A manual of diseases of the nervous system. onecase curious rhythmical movements at the wrist and elbow were pre-sent, suggesting those of canine chorea, and probably of significance,as we shall see when we come to discuss the morbid anatomy. Con-tractions may be superadded, and bedsores, cystitis, and gradualexhaustion sooner or later lead to a fatal issue. Besides the symptoms enumerated there may of course be the usualsymptoms of profound anaemia—such as reduction in haemoglobinand number of corpuscles, enlargement of spleen, and haemorrhages inthe retinae and elsewhere. But, as has been
. A manual of diseases of the nervous system. onecase curious rhythmical movements at the wrist and elbow were pre-sent, suggesting those of canine chorea, and probably of significance,as we shall see when we come to discuss the morbid anatomy. Con-tractions may be superadded, and bedsores, cystitis, and gradualexhaustion sooner or later lead to a fatal issue. Besides the symptoms enumerated there may of course be the usualsymptoms of profound anaemia—such as reduction in haemoglobinand number of corpuscles, enlargement of spleen, and haemorrhages inthe retinae and elsewhere. But, as has been stated, obvious anaemiais not constant in the condition under notice. * ? Deut. Med. Wochenschr., * Arch, f. Psych., xxv, Brain, 1894.§ • Trans., Brit. Med. Journ., 1897.•ir Lancet, 1898.•• Journ. of Nerv. and Ment. Diseases, 1891. SCLEROSIS FROM TOXIO BLOOD-STATES. 515 MoEBiD Anatomy.—The changes found in the spinal cord aresuriously uniform (Fig. 137). In the cervical region they are usually. ftff. 187.—SLowinp: sclerosis occurring in a case of profound sclerotic areas are decolourised. Note in the lumbar cord the com-parative escape of the septo-mar^^inal and coma-comniiasilXiil tractsA, cervicaL B, dorsal. C* Inmbar. 516 SPINAL COED. wide-spread, and are found in anterior, lateral, and postc:L,.ur columns;the part of the anterior column chiefly affected, and also of tlie lateral,being tlie pyramidal tracts, although th change is not restricted tothese in either region. In the dorsal region the change is still exten-sive, but there is a gradual diminution downwards, so that in thelumbar region the sclerosis is much less wide-spread and less completein character. In this region the part of the posterior column next thecommissure is usually spared, as also that close to the posterior septum—the septo-marginal tract of probably endogenous fibres alreadyalluded to (p. 218). It is well seen in the accompanying illustra
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