. The American journal of roentgenology, radium therapy and nuclear medicine . shadows willbe found over the peripheral distribution ofsome of the upper lobe bronchi. The bron-chial twig or branch involved may be smalland the shadow correspondingly limited, orthe area involved may be large, even anentire lobe; but the shadow will be a peri-pheral shadow and will be in the upper lobe,whether the tuberculosis is of the minimaldegree, barely perceptible on the radiograph,or whether it is of the most extensive de- served and which others, no doubt, can interrelation between tuberculosis a


. The American journal of roentgenology, radium therapy and nuclear medicine . shadows willbe found over the peripheral distribution ofsome of the upper lobe bronchi. The bron-chial twig or branch involved may be smalland the shadow correspondingly limited, orthe area involved may be large, even anentire lobe; but the shadow will be a peri-pheral shadow and will be in the upper lobe,whether the tuberculosis is of the minimaldegree, barely perceptible on the radiograph,or whether it is of the most extensive de- served and which others, no doubt, can interrelation between tuberculosis andsvphilis has been in the minds of clinicianssince tuberculosis was isolated from otherkmg diseases and established as a clinicalentity. The effects of the acquirement oftuberculosis by a syphilitic person, and viceversa, have been discussed at length by manywriters, but without definite conclusions,due, no doubt, to the uncertainty regard-ing syphilitic infection in the lung. Untilthere was a clear conception of lung syphilisitself, naturally no very definite idea regard-. Fig. 5 (Patient 3134). Extensive syphilitic infiltrationof right base. Almost entirely resolved followingtwo injections of salvarsan. gree, involving all branches of both upperlobes. When tuberculosis spreads from theupper lobes into the lower areas, or whenit invades the central or basal regions pri-marily, we may expect to find an accompany-ing or antecedent mixed infection, producingan atypical localization of the tuberculouslesions. There may be exceptions to this rule,but it forms the clinical basis of our inter-pretation of tuberculous shadows, and manyobservations have only strengthened our con-viction that this is a safe working basis,in spite of exceptions which we have ob- Fig. 6 (Patient 8675). Syphilitic sclerosis of king andpleura. Wassermann positive. Autopsy showedcomplete destruction of lung tissue, with cicatrica-tion, and large annular aneurysm of aortic arch. ing its combination with tube


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