. Colchicine in agriculture, medicine, biology, and chemistry. Colchicine; Colchicine. Embryonic Growth in Animals 205 toxicity of colchicine, and has been described under various experi- mental conditions and with other mitotic ;^^ With less toxic colchicine derivatives, spindle inactivation is apparent in a few horns. Depending on the doses injected, recovery is possible, or considerable cellular damage may be found. Binucleated spermatids may result from the spermatogonia! mitoses during recovery assuming the "dis- tributed" type with two nearly equal groups of chromo
. Colchicine in agriculture, medicine, biology, and chemistry. Colchicine; Colchicine. Embryonic Growth in Animals 205 toxicity of colchicine, and has been described under various experi- mental conditions and with other mitotic ;^^ With less toxic colchicine derivatives, spindle inactivation is apparent in a few horns. Depending on the doses injected, recovery is possible, or considerable cellular damage may be found. Binucleated spermatids may result from the spermatogonia! mitoses during recovery assuming the "dis- tributed" type with two nearly equal groups of chromosomes (cf. Chapter 2). In fowls also, colchicine may induce severe degenerative changes in testicular cells. These are followed by regeneration seven days No polyploid spermatozoa have been reported in vertebrates. On the contrary, in the insect Triatomn infestans (order: Hemiptera), colchicine not only inhibits the spindle function, but as a consequence, modifies considerably the size of the spermatids (Fig. ) . This is observed after nine days, wlien all spermatogenetic cells have dis- appeared. The simple numerical relations between nuclear sizes are a strong evidence in favor of polyploidy, although the exact inter- pretation of these facts awaits further research.^^ Control. Colchicine 9 days. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Eigsti, O. J. (Orie Jacob), 1908-; Dustin, Pierre. Ames, Iowa State College Press
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