. Ciba Foundation symposium on drug resistance in micro-organisms: mechanisms of development. Drug resistance in microorganisms. Inheritance in Single Bacterial Cells 67 Now taking the action of penicillin first, Fig. 6 shows a group of organisms transferred to penicillin-agar. Just as the morphological effect of the drug varies with concentration, so if the concentration is kept constant individual cells in a culture will be influenced differently. The cell on the right of m I rp^^irp. 'iW^ ^A^^ Key . (K Long form alive A L°"g ^^^'^ ^^^^ • ^° growth, autolysed Fig. 7. The effect of 10 u.

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. Ciba Foundation symposium on drug resistance in micro-organisms: mechanisms of development. Drug resistance in microorganisms. Inheritance in Single Bacterial Cells 67 Now taking the action of penicillin first, Fig. 6 shows a group of organisms transferred to penicillin-agar. Just as the morphological effect of the drug varies with concentration, so if the concentration is kept constant individual cells in a culture will be influenced differently. The cell on the right of m I rp^^irp. 'iW^ ^A^^ Key . (K Long form alive A L°"g ^^^'^ ^^^^ • ^° growth, autolysed Fig. 7. The effect of 10 u. penicillin/ml. on the individual cells of nine micro- cultures, grown from nine members of a clone of sixteen cells. (Hughes W. H. (19556), J. gen. Microbiol., 12, 269.). Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation; Wolstenholme, G. E. W. (Gordon Ethelbert Ward); O'Connor, Cecilia M. (Cecilia Mary), 1927-. Boston, Little, Brown

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