. Biological structure and function; proceedings. Biochemistry; Cytology. Integrated Oxidations in Isolated Mitochondria J. B. Chappell* Department of Biochemistry, Uuirersity of Cambridge, England It appears that, in intact mitochondria, a straightforward reduction of pyridine nucleotide by substrate, followed by reoxidation of the reduced nucleotide by the cytochrome system does not occur without complications Ag-AgCI 0-5M KCI Pt electrode. Perspex disc Tlea' O' ring supporting membrane -Support for vessel 1cm Fig. I. The Clark oxygen electrode adapted for following mitochondrial respiration
. Biological structure and function; proceedings. Biochemistry; Cytology. Integrated Oxidations in Isolated Mitochondria J. B. Chappell* Department of Biochemistry, Uuirersity of Cambridge, England It appears that, in intact mitochondria, a straightforward reduction of pyridine nucleotide by substrate, followed by reoxidation of the reduced nucleotide by the cytochrome system does not occur without complications Ag-AgCI 0-5M KCI Pt electrode. Perspex disc Tlea' O' ring supporting membrane -Support for vessel 1cm Fig. I. The Clark oxygen electrode adapted for following mitochondrial respiration. arising because of subsequent events at the substrate level. This paper represents an attempt to justify this statement. All the investigations reported have been performed w-ith the Clark oxygen electrode set up as * Present address: TJie Johnsnii Foundation, University of Pennsylvania, Philadelphia, Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original IUB/IUBS International Symposium (1st : 1960 : Stockholm); International Union of Biochemistry; International Union of Biological Sciences; Goodwin, T. W. (Trevor Walworth); Lindberg, Olov, 1914-. London, New York, Academic Press
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