A treatise on Bright's disease and diabetes, with especial reference to pathology and therapeuticsIncluding a section on retinitis in Bright's disease . n. They may be studied from their beginnings in thecortex, or backwards as it were, from their terminations in thedischarging-tubes on the papillae. Selecting the former, thelittle granules visible to the naked eye in the labyrinth arethe beginnings of the uriniferous tubules. These are sphericaldilatations, .15 to .2 mm. (y e o ^^ 125 inch) in diameter, formedof basement membrane lined by a mosaic of pavement epithe-lium. They are the so-call
A treatise on Bright's disease and diabetes, with especial reference to pathology and therapeuticsIncluding a section on retinitis in Bright's disease . n. They may be studied from their beginnings in thecortex, or backwards as it were, from their terminations in thedischarging-tubes on the papillae. Selecting the former, thelittle granules visible to the naked eye in the labyrinth arethe beginnings of the uriniferous tubules. These are sphericaldilatations, .15 to .2 mm. (y e o ^^ 125 inch) in diameter, formedof basement membrane lined by a mosaic of pavement epithe-lium. They are the so-called Malpighian capsules (1), Fig. 4,and are continuous, by a necklike construction (2), with theproximal convoluted tubule (3), which winds towards theadjacent medullary ray; reaching which, it passes verticallydownward as the spiral tube (4) of Schachowa. These por-tions are all in the cortex, A. At the junction of the cortexand the border layer, the spiral tubule becomes suddenly nar- STRUCTURE OF THE KIDNEY. 21 rower, and (lij)s down tlirough this layer, B, as the descendinglimh (5) of Henles loop, the loop itself (6) being formed in the Fig. 4. Diagrammatic representation of the course of two urinary tubules.—After Klkin and Noble Smith. papillary layer, C. Ee-entering the boundary layer, the tubebecomes suddenly enlarged and slightly wavy in its course,forming the first thick portion (7) of the ascending limb of 22 brights disease. Henles loop. At the middle of the boundary layer it againbecomes narrower and spiral in its course, forming the spiralpart (8) of the ascending limb. The ascending limb nowre-enters the cortex in the medullary ray, again becoming nar-rower, though not of uniform diameter, and straighter, butstill slightly wavy in its course (9). Sooner or later, after re-entering the cortex, the tubule dips away from the medullaryray and passes into the labyrinth as a tube irregular in outline,breadth, and course, whence it is called the irregular tubule (10).F
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Keywords: ., bookcentury1800, bookdecade1880, bookpublisherphila, bookyear1881