The Journal of nervous and mental disease . e pineal gland or the hypophysis, those of priapism and of skeletalgrowth. In none of the 18 cases of tumor of the crus heretoforepublished, were such symptoms mentioned. As neither of theseglands was abnormal, as shown at the necropsy, were they produced 5o8 WALTER TIM ME by the pressure within the third ventricle transmitted to the pinealgland or to the hypophyseal stalk, or were they originated by directpressure of the left crus cerebri (which centrally encroached on themiddle line) upon the hypophysis, and superiorly against the pineal?As the ven


The Journal of nervous and mental disease . e pineal gland or the hypophysis, those of priapism and of skeletalgrowth. In none of the 18 cases of tumor of the crus heretoforepublished, were such symptoms mentioned. As neither of theseglands was abnormal, as shown at the necropsy, were they produced 5o8 WALTER TIM ME by the pressure within the third ventricle transmitted to the pinealgland or to the hypophyseal stalk, or were they originated by directpressure of the left crus cerebri (which centrally encroached on themiddle line) upon the hypophysis, and superiorly against the pineal?As the ventricles were hardly distended, it is fair to assume thatthe increased mass of the left crus cerebri was. the irritative cause ofthese symptoms. Furthermore the signs of increased intracranialpressure came on after the growth ])henomena had appeared andtherefore these could not have depended on this general pressureincrease. Another, though very remote possibility, is that the fibersof the commissura habenularum (some of which penetrate and. A transverse sectit/ii uf brain showing the enlarged left cms cerebriimpinging against the stalk of the hypophysis , and against the pinealgland dorsally. The very slight distension of the ventricles is also to beremarked. become part of the pineal gland), in their further course from theglandula habemiUe to the glandula interpedtmcularis as the interi)cduncularis, arc interfered with in their coursethrotigh the crus by the tumor, thus affecting ihe function of thepineal. In such an event, however, all ttimors of the crtis shouldshow similar symptoms—which they do not. These fibers more-over are presumed to be merely vestigial in character. These remarks are of course based upon the assumption thatinterference with either the hypo]>hysis or the pineal gland, orperhaps both, influences the evolution and control of skeletal growthand sexual precocity. TUMOR INVOLVING CRUS CEREBRI 509 The autopsy by Dr. Casam


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic