. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. MOLLUSCAN EGG-LAYING HORMONES 213 Table I (Continued) 18 19 23 24 25 26 28 29 30 31 32 33 34 35 Gin He Arg Glu Arg Gin Arg Tyr Leu Ala Asp Leu Arg Gin Arg Leu Leu Glu Lys-NH2 Gin He Arg Glu Arg Gin Arg Tyr Leu Ala Asp Leu Arg Gin Arg Leu Leu Glu Lys-NH, Gin He Gin Ala Arg Gin Arg Cys Leu Ala Ala Leu Arg Gin Arg Leu Leu Asp Leu-NH: Gin He Gin Ala Arg Arg Arg Cys Leu Ala Ala Gin He Gin Ala Arg Arg Arg Cys Leu Asp Ala Gin Lys Gin Glu Arg Glu Lys Tyr Leu Ala Asp Leu Arg Gin Arg Leu Leu Asp Leu-NH2 Leu Arg Gin Arg Leu Leu Asp Leu
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. MOLLUSCAN EGG-LAYING HORMONES 213 Table I (Continued) 18 19 23 24 25 26 28 29 30 31 32 33 34 35 Gin He Arg Glu Arg Gin Arg Tyr Leu Ala Asp Leu Arg Gin Arg Leu Leu Glu Lys-NH2 Gin He Arg Glu Arg Gin Arg Tyr Leu Ala Asp Leu Arg Gin Arg Leu Leu Glu Lys-NH, Gin He Gin Ala Arg Gin Arg Cys Leu Ala Ala Leu Arg Gin Arg Leu Leu Asp Leu-NH: Gin He Gin Ala Arg Arg Arg Cys Leu Ala Ala Gin He Gin Ala Arg Arg Arg Cys Leu Asp Ala Gin Lys Gin Glu Arg Glu Lys Tyr Leu Ala Asp Leu Arg Gin Arg Leu Leu Asp Leu-NH2 Leu Arg Gin Arg Leu Leu Asp Leu-NH, Leu Arg Gin Arg Leu Leu Asn Lys-NH, Gin His Trp Leu Arg Glu Arg Gin Glu Glu Asn Leu Arg Arg Arg Phe Leu Glu Leu-NH: Each of the ELH-family genes expressed in the atrial gland encodes a large polyprotein precursor. Two of the precursors, preproA and preproB, are diagrammed in Figure 1; the diagrams are based on nucleotide sequence analyses of genomic and cDNA clones (Scheller et ai. 1983; Mahon et a/., 1985) and have been modified by peptide sequence analyses (Heller et al, 1980; Nagle et ai. 1986, 1988c; Rothman et 1986). The products that have been isolated and chemically characterized are summarized in Table IV. preproELH Signal preproB preproA. Signal A-NTP Figure 1. Schematic diagram of Aplysia calijornica preproELH, preproB, and preproA as predicted from nucleotide sequence analyses of genomic and cDNA clones (Scheller et 1983; Mahon el ai. 1985) and modified by peptide studies (Nagle et 1986, 1988c; Rothman et 1986). Signal peptides are represented by hatched boxes. Peptides that have been identified in extracts or releasates are indicated by black boxes and have been labeled. Known or predicted mono-, di-, tri-, and tetrabasic cleavage sites, as well as the Gly-Lys-Arg signal for COOH-terminal amidation, are shown. Abbreviations are denned in a footnote on the first page of this Please note that these images are extracted from scanned pag
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
