. The elements of pathological histology with special reference to practical methods . t so frequent (i). In consequence of the changes in the glomerular and otherblood-vessels, as well as probably owing to shrinkage of thenewly-formed connective tissue, there results an atrophy of theurinary tubules {a), which become narrower and their epithelialcells lower, until finally the latter are entirely destroyed. Theexternal tokens of this atrophy are numerous depressions {B) onthe surface of the organ, between which little granules project {A),the latter containing tubules which are still normal or
. The elements of pathological histology with special reference to practical methods . t so frequent (i). In consequence of the changes in the glomerular and otherblood-vessels, as well as probably owing to shrinkage of thenewly-formed connective tissue, there results an atrophy of theurinary tubules {a), which become narrower and their epithelialcells lower, until finally the latter are entirely destroyed. Theexternal tokens of this atrophy are numerous depressions {B) onthe surface of the organ, between which little granules project {A),the latter containing tubules which are still normal or even hyper-trophic, , dilated (Ji) and lined with enlarged epithelial , the capsule of the kidney is greatly thickened and 802 THE KIDNEYS permeated by large blood-vessels and lymphatics. At this stage,owing to partial compression of the tubules by the shrinking con-nective tissue, retention of urine in the canaliculi (perhaps also inthe cavities of the Bowmans capsules) not uncommonly results,and ultimately a formation of cysts, sometimes very numerous, which. Fig. 140.—Chronic Interstitial Nephritis in the stage of atrophy, x 77. (Hsema-toxyliu and eosin.) A, Superficial granules ; B, Depression of surface ; a, Atrophied andpartially compressed urinary tubules ; 6, Obliterated glomeruli, partly with concentriclamination of their connective tissue ; c, Thickened interstitial connective tissue, inpart infiltrated with small cells; d, Dilated blood-vessel; e, Artery with thickened(hyaline degenerated?) wall;./, Glomeruli in the cavities of whose capsules are collecteda finely-granular exudation, and partly also red corpuscles ; (/, Glomerulus with thickenedcapsule ; h, Dilated urinary tubule containing finely granular masses ; i, Hyaline cast ina urinary tubule; k. Dilatation of a virinary tubule with colloid matter (small colloid cyst). when very small may have colloid contents {k) but otherwise arefilled with a thin fluid, and which are lined with low c
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895
