Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . ^infiltration is deeper. Thepatches are elevated, ede-matous, and surroundedby a slight zone of redness;at first the agminated nodeis intensely engorged anddeeply colored, but laterthe tension within the|)atch rises, the vessels areoccluded by hyalinethrombi, less blood enters,circulation is arrested, ne-crosis occurs, the sloughseparates, and an ulcerresults. The depth of theulcer is dependent uponthe extent of the necrosis:it may involve only a partof the mucosa, but more commonly t


Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . ^infiltration is deeper. Thepatches are elevated, ede-matous, and surroundedby a slight zone of redness;at first the agminated nodeis intensely engorged anddeeply colored, but laterthe tension within the|)atch rises, the vessels areoccluded by hyalinethrombi, less blood enters,circulation is arrested, ne-crosis occurs, the sloughseparates, and an ulcerresults. The depth of theulcer is dependent uponthe extent of the necrosis:it may involve only a partof the mucosa, but more commonly the entire thickness of the epitheliallayer is destroyed, and the submucosa or muscularis is exposed. Theedge of the ulcer is irregular, swollen, and, it may be, undermined;the base, after the slough has completely disappeared, is clean and. Fig. 355.—Small Intestine. Typhoid Ulcer during theEarly Part of Third Week of the Disease. (Naturalsize.) The long axis of the ulcer corresponds to that of the bowel; thebase of the ulcer still contains the slough, or necrotic tissue,which is nearly ready to be thrown off; its ragged and fissuredsurface is well shown. ^ Brit. Med. Jour., April 9, 1904. ^ Arch. Gen. de Med., Sept. i, IQ03. See also Atlassoff, Annales de , Nov. 25, 1904, p. 701 For literature on mori^id anatomy of Mallory,Jour, of Exper. Med., vol. iii, p. 611. Longcope, Bi:ll. of theAver Clinical Laboratory of the Penna. Hospital, Jan., 1903, No. 2. Baer,Amer. Jour. Med. Sci., May, 1904, p. 787. For complications of typhoid seeKeen, Surgical Complications and Sequels of Typhoid Fever, 1898. AlsoHare, The Medical Complications, Accidents, and Sequels of Typhoid or EntericFever, 1902. ALIMKNTAkV CAN A J 2() smooth. It the slou},hini, i)rocess be attended by inliltration and vas-cular sta


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