A manual of modern surgery : an exposition of the accepted doctrines and approved operative procedures of the present time, for the use of students and practitioners . e pois-onous principle be absorbed. A recentwound or one covered with unhealthygranulations allows rapid absorption of thepoisonous substances, while healthy granu-lations seem to act as a barrier to septicinfection. The blood in septicemic condi-tions is less coagulable than in health andtarry; and the red corpuscles show a ten-dency to congregate in irregular masses,and to undergo ante-mortem disintegration. In addition, conge
A manual of modern surgery : an exposition of the accepted doctrines and approved operative procedures of the present time, for the use of students and practitioners . e pois-onous principle be absorbed. A recentwound or one covered with unhealthygranulations allows rapid absorption of thepoisonous substances, while healthy granu-lations seem to act as a barrier to septicinfection. The blood in septicemic condi-tions is less coagulable than in health andtarry; and the red corpuscles show a ten-dency to congregate in irregular masses,and to undergo ante-mortem disintegration. In addition, congestionsof organs and stasis of the blood current or thrombosis are frequentlyobserved. The autopsy frequently shows softening and degenerationof the liver and spleen, ecchymosis and even inflammation of theserous membranes, and changes in the glands and mucous membraneof the intestines. The fluids of the body especially perhaps thosefrom the liver and spleen, are infectious, except in sapremia. Cul-tures are easily made from them, and pricks made with the instru-ments used by the surgeon or pathologist are liable to cause infectionof the injured person (Fig. 9).. Diagram of a hemorrhagic in-farct : a, artery obliterated by auembolus (e); v, vein filled with asecondary thrombus (th); 1, centerof infarct which is becoming disin-tegrated ; 2, area of extravasation ;3, area of collateral hyperemia. () CA USES. 59 Pyemia may be provisionally considered as septicemia with the ad-dition of disseminated spots of inflammation and suppuration. Theseconsist of metastatic abscesses in lungs, liver, spleen and other viscera,due to embolism and bacterial infection ; and suppuration in joint cav-ities or inflammation of cellular or serous tissues, caused either by em-bolism or the blood change. Metastatic abscesses commence as small,reddish and usually pyramidal sections of solidified tissue, which arefound most frequently near the periphery of the lungs, liver and soon br
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